The normal range is between 1.0 and 1.5 ng/ml. An abnormal rise: A PSA score may also be considered abnormal if it rises a certain amount in a single year. For example, if your score rises more than 0.35 ng/ml in a single year, your doctor may recommend further testing. Your prostate-specific antigen (PSA) levels should usually be pretty low. PSA is a protein your prostate gland produces. High levels of PSA circulating in your blood may indicate prostate Prostate-specific antigen (PSA) is a protein produced by the glandular tissue of the prostate (a walnut-sized gland just below the bladder and in front of the rectum in males). PSA levels can be detected in the blood, urine, or semen. Blood PSA testing is used as a screening test for prostate cancer. O5hN.